个人简介
郝宏东,1984年11月生,山西大同人,副教授,博士生导师
工作经历
2017.06-至今,金沙检测线路js69 金沙检测线路js69,副教授
2013.12-2017.02,德国慕尼黑大学化学系博士后,导师:Dirk Trauner教授
2011.09-2013.11 北京大学深圳研究生院 化学生物学与生物技术学院 博士后,导师:杨震 教授
受教育经历
2006.09-2011.06,中国科学院上海有机化学研究所 理学博士 导师:伍贻康 研究员
2002.09-2006.06,沈阳药科大学药学理科基地班理学学士 导师:程卯生 教授
研究方向
活性天然产物的全合成及药物化学研究;有机合成方法学的开发及应用。
迄今,在 JACS , Org. Lett , Chem. Eur. J 等杂志上发表论文11篇,代表性工作先后被Organic Chemistry Portal, ChemistryViews等Highlight。
科研课题项目
金沙检测线路js69科研启动基金(60万)
开设课程
药物化学
主要科研成果与学术论文
1. Hao, H. D.; Trauner, D*. Furans as Versatile Synthons: Total Syntheses of Caribenol A and Caribenol B. J. Am.Chem. Soc .2017, 139 , 4117- 4122.
(This paper has been ranked as one of the top 20 "Most Read Articles in the month" in J. Am. Chem. Soc.)
Highlight by X-MOL http://www.x-mol.com/news/5768
2. Chang, Y. Y.; Shi, L. L.; Huang, J.; Shi, L. L.; Zhang, Z, C.; Hao, H. D*.; Gong, J*.; Yang, Z*. Stereoselective Total Synthesis of 5-epi-Cyanthiwigin I via an Intramolecular Pauson-Khand Reaction as the Key Step. Org. Lett . 2018, 20 , 2876-2879.
3. Hao, H. D.; Wittlin, S.; Wu, Y*. Potent Antimalarial 1,2,4-trioxanes via Perhydrolysis of
Epoxides. Chem. Eur. J. 2013, 19 , 7605-7619.
Highlighted in ChemistryViews "New Route to Antimalarial Artemisinin"
http://www.chemistryviews.org/details/ezine/4515011/New_Route_to_Antimalarial_Artemisinin.html
4. Hao, H. D.; Li, Y.; Han, W. B.; Wu, Y*. A hydrogen Peroxide Based Access to Qinghaosu
(Artemisinin). Org. Lett. 2011, 13 , 4212-4215.
Highlighted in Org. Chem. Highlights "Natural Product Synthesis by C-H Functionalization", June, 2012
http://www.organic-chemistry.org/Highlights/2012/11June.shtm
5. Chen, H.-J.; Hao, H.D.; Wu, Y*. Conversion of Dihydroartemisinic Acid into Dihydro-epi-
deoxyarteannuin B. Eur. J. Org. Chem . 2015, 4423-4427.
6. Chen, H.-J.; Han, W.-B.; Hao, H. D.; Wu, Y*. A Facile and Scalable Synthesis of
Qinghaosu (Artemisinin). Tetrahedron 2013, 69, 1112-1114.
7. Chen, H.-J.; Hao, H. D.; Wu, Y*. A Clear-Cut Synthesis of Arteannuin O. Chin. J. Chem.
2013, 31 , 139-142.
8. Li, Y.; Hao, H. D.; Wittlin, S.; Wu, Y*.Simple Analogues of Qinghaosu. Chem. Asian. J .
2012, 7 , 1181-1186.
9. Zhang, Y.; Hao, H. D.; Wu, Y*. An 1,2-Elimination Approach to the Enantioselective
Synthesis of 1,3-Disubstituted Linear Allenes. Synlett . 2010, 905-908.
10. Li, Y.; Hao, H. D.; Wu, Y*. Facile Ring-Opening of Oxiranes byH2O2 Catalyzed by
PhosphomolybdicAcid. Org. Lett. 2009, 11 , 2691-2694.
11. Li, Y.; Hao, H. D.; Zhang, Q.; Wu, Y*. A Broadly Applicable Mild Method forthe Synthesis
of gem-Diperoxides fromCorresponding Ketones or1,3-Dioxolanes. Org. Lett . 2009, 11 ,
1615-1618.
联系方式
通讯地址:金沙检测线路js69金沙检测线路js69 邮编:712100
电话:18092456335
邮箱:hongdonghao@nwafu.edu.cn或hdhao_spu@163.com
课题组网站:http://haogroup.sxl.cn/
欢迎对有机合成感兴趣的同学进行实习研究。